Government Degree Science and Commerce College for Women, F.B Area, Block-16 is a public college for women in Karachi, Sindh, Pakistan. The college was established in 1978 and is affiliated with the University of Karachi.

The college offers undergraduate programs in science, commerce, and education. The science programs include biology, chemistry, physics, and mathematics. The commerce programs include accounting, finance, and marketing. The education programs include early childhood education, primary education, and secondary education.

The college has a well-equipped library, computer labs, and science labs. The college also has a hostel for students who live outside of Karachi.

The Government Degree Science and Commerce College for Women is a well-respected college in Karachi. The college has a strong academic reputation and its graduates are in high demand by employers.

The Government Degree Science and Commerce College for Women, F.B Area, Block-16, offers various scholarships to deserving students based on merit and need.